SCHEMBL2184674

SCHEMBL2184674

CCCCCCCCC=CCCCCCCCCOP(=O)(CCCCCCCCC=CCCCCCCCC)OCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 10/20 0.62
LPAR2 Q9HBW0 8/20 0.62
LPAR1 Q92633 5/20 0.62
FAAH O00519 3/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
PLA2G4A P47712 1/20 0.49
PAFAH1B2 P68402 1/20 0.49
KMT2A Q03164 1/20 0.49
MGLL Q99685 1/20 0.49
ABHD6 Q9BV23 1/20 0.49
TRPV1 Q8NER1 1/20 0.47
P2RY10 O00398 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184672 1.00 LPAR3 (0.62) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL9659826 1.00 LPAR3 (0.62) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL9659819 1.00 LPAR3 (0.62) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL9660268 0.96 LPAR3 (0.59) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL9660262 0.96 LPAR3 (0.59) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL30906162 0.92 ALDH1A1 (0.56) LPAR3LPAR2LPAR1FAAHMEN1
SCHEMBL18116580 0.90 LPAR3 (0.55) LPAR3LPAR2LPAR1FAAHTRPV1
SCHEMBL11447220 0.89 LPAR3 (0.59) LPAR3LPAR2LPAR1FAAH
SCHEMBL11671731 0.89 LPAR3 (0.59) LPAR3LPAR2LPAR1FAAH
SCHEMBL2184531 0.89 LPAR3 (0.59) LPAR3LPAR2LPAR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343355-B1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2016-12-07 EP disclosed
EP-1544279-B1 LUBRICATING COMPOSITION NIPPON OIL CORP (JP) 2016-09-28 EP disclosed
EP-1686167-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2016-05-25 EP disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
US-7696137-B2 Lubricating oil compositions NIPPON OIL CORPORATION (JP) 2010-04-13 US disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
US-20050143266-A1 Lubricating oil compositions NIPPON OIL CORPORATION 2005-06-30 US disclosed
EP-1544279-A1 LUBRICATING COMPOSITION Nippon Oil Corporation (JP) 2005-06-22 EP disclosed