Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258282 | 0.89 | STS (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17956487 | 0.89 | STS (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17956419 | 0.86 | CTSL (0.33) | ALDH1A1CTSLCTSBCTSKGAA | |
| SCHEMBL20258280 | 0.85 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL20258276 | 0.80 | USP30 (0.37) | ALDH1A1 | |
| SCHEMBL18044440 | 0.80 | USP30 (0.37) | ALDH1A1 | |
| SCHEMBL17956400 | 0.80 | USP30 (0.37) | ALDH1A1 | |
| SCHEMBL20258290 | 0.75 | USP30 (0.36) | ALDH1A1 | |
| SCHEMBL17956503 | 0.75 | USP30 (0.36) | ALDH1A1 | |
| SCHEMBL20258292 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050883-B1 | PRODUCTION METHOD FOR DIAZABICYCLOOCTANE DERIVATIVES AND INTERMEDIATES | MEIJI SEIKA PHARMA CO LTD (JP) | 2020-04-22 | — | — | EP | disclosed |