Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496043 | 1.00 | GAA (0.49) | GAAALDH1A1HPGDHTTMEN1 | |
| SCHEMBL29496196 | 0.85 | ALDH1A1 (0.56) | GAAALDH1A1HPGDMEN1TSHR | |
| SCHEMBL21847851 | 0.85 | ALDH1A1 (0.56) | GAAALDH1A1HPGDMEN1TSHR | |
| SCHEMBL31581604 | 0.82 | HTT (0.51) | GAAALDH1A1HPGDHTTMEN1 | |
| SCHEMBL31644154 | 0.81 | ALDH1A1 (0.49) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31644215 | 0.81 | ALDH1A1 (0.49) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL21847824 | 0.80 | NPSR1 (0.52) | GAAALDH1A1HPGDMEN1TSHR | |
| SCHEMBL29496233 | 0.80 | NPSR1 (0.52) | GAAALDH1A1HPGDMEN1TSHR | |
| SCHEMBL22890816 | 0.76 | ALDH1A1 (0.47) | GAAALDH1A1HPGDMEN1TSHR | |
| SCHEMBL31644323 | 0.75 | ALDH1A1 (0.49) | GAAALDH1A1HPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020134-A | Heterocyclic carbonyl derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-05-20 | — | — | CN | disclosed |
| US-20240190869-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2024-06-13 | — | — | US | disclosed |
| US-11905284-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | PFIZER INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2023-06-22 | — | — | US | disclosed |
| CN-109641898-B | 5, 7-dihydro-pyrrolo-pyridine derivatives for the treatment of neurological and neurodegenerative diseases | 辉瑞公司 | 2022-04-08 | — | — | CN | disclosed |
| US-20210309659-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210309659-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2021-10-07 | — | — | US | disclosed |
| EP-3478679-B1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | PFIZER (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3478679-B1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | PFIZER (US) | 2021-04-21 | — | — | EP | disclosed |
| US-20200207762-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2020-07-02 | — | — | US | disclosed |
| US-20200207762-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2020-07-02 | — | — | US | disclosed |
| US-10604519-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | PFIZER INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-10604519-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | PFIZER INC. (US) | 2020-03-31 | — | — | US | disclosed |
| EP-3478679-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | Pfizer Inc (US) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018002760-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES | PFIZER INC. (US) | 2018-01-04 | — | — | WO | disclosed |
| US-20180002331-A1 | 5,7-Dihydro-Pyrrolo-Pyridine Derivatives | PFIZER INC. (US) | 2018-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190869-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-20210309659-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-20200207762-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-20230192690-A1 | 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-20180002331-A1 | 5,7-Dihydro-Pyrrolo-Pyridine Derivatives | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-10604519-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
| US-11905284-B2 | 5,7-dihydro-pyrrolo-pyridine derivatives | CHRM1, CHRM5, CHRM2 | GAA 2070/4885ALDH1A1 754/4885HPGD 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.