Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595120 | 0.84 | FFAR1 (0.50) | FFAR1FFAR4 | |
| SCHEMBL2767456 | 0.84 | ALDH1A1 (0.48) | FFAR1ABCB1MTNR1ACTSLCTSB | |
| SCHEMBL3587465 | 0.81 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL9366721 | 0.79 | NPC1 (0.47) | ABCB1 | |
| SCHEMBL21037538 | 0.77 | NPC1 (0.48) | ABCB1 | |
| SCHEMBL21847981 | 0.77 | ABCB1 (0.46) | FFAR1ABCB1MTNR1ACTSLCTSB | |
| SCHEMBL10532890 | 0.76 | KDM4E (0.55) | FFAR1 | |
| SCHEMBL7822529 | 0.76 | FFAR4 (0.73) | FFAR1FFAR4MTNR1A | |
| SCHEMBL9179664 | 0.76 | BRS3 (0.53) | — | |
| SCHEMBL15318884 | 0.76 | MAOB (0.54) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639824-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-04-22 | — | — | EP | disclosed |