Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.60 |
| ▸ | PGR | P06401 | 2/20 | 0.60 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.60 |
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.60 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682762 | 1.00 | SHBG (0.79) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL22100655 | 1.00 | SHBG (0.79) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL2545773 | 1.00 | SHBG (0.79) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL2733387 | 0.88 | SHBG (1.00) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL9172697 | 0.88 | SHBG (1.00) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL10274070 | 0.88 | SHBG (1.00) | SHBGCYP3A4TSHRTHPOHIF1A | |
| Clostebol SCHEMBL4437252 | 0.87 | SHBG (0.76) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL10944734 | 0.87 | SHBG (0.76) | SHBGCYP3A4TSHRTHPOHIF1A | |
| Clostebol SCHEMBL146712 | 0.87 | SHBG (0.76) | SHBGCYP3A4TSHRTHPOHIF1A | |
| SCHEMBL28944454 | 0.87 | SHBG (0.76) | SHBGCYP3A4TSHRTHPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070296-A1 | COMBINATIONS WITH A C-19 STEROID FOR TREATING CANCERS | CURADIS GMBH (DE) | 2020-04-09 | — | — | WO | disclosed |