Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952557 | 0.77 | HRH3 (0.41) | HRH3HSD11B1 | |
| Hydrochloric Acid SCHEMBL20475439 | 0.76 | HRH3 (0.41) | HRH3HSD11B1 | |
| SCHEMBL20533530 | 0.74 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL549489 | 0.73 | HSD11B1 (0.39) | HRH3HSD11B1 | |
| SCHEMBL18367208 | 0.72 | HRH3 (0.37) | HRH3EBPKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2700926 | 0.72 | HSD11B1 (0.39) | HRH3HSD11B1 | |
| Hydrochloric Acid SCHEMBL549316 | 0.72 | HSD11B1 (0.39) | HRH3HSD11B1 | |
| Hydrochloric Acid SCHEMBL28578394 | 0.71 | HRH3 (0.36) | HRH3KDM4EL3MBTL1 | |
| SCHEMBL4719346 | 0.70 | HSD11B1 (0.40) | HRH3HSD11B1 | |
| SCHEMBL5629411 | 0.70 | HSD11B1 (0.40) | HRH3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063855-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |