SCHEMBL21851702

SCHEMBL21851702

O=C(Cc1ccccc1Cl)Cc1ccccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
CTBP2 P56545 1/20 0.50
ALDH1A1 P00352 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
CYP2A6 P11509 1/20 0.48
APAF1 O14727 1/20 0.47
TDP2 O95551 1/20 0.47
NSD2 O96028 1/20 0.47
MAPT P10636 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
UBA2 Q9UBT2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
PKM P14618 1/20 0.44
HIF1A Q16665 1/20 0.44
DPP4 P27487 1/20 0.44
FOLH1 Q04609 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CNR2 P34972 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437801 0.89 KMT2A (0.60) KMT2AALDH1A1DPP4FOLH1RAB9A
SCHEMBL31365969 0.85 CTBP2 (0.58) KMT2ACTBP2ALDH1A1APAF1TDP2
SCHEMBL6194349 0.85 CTBP2 (0.58) KMT2ACTBP2ALDH1A1APAF1TDP2
SCHEMBL10015436 0.82 KMT2A (0.53) KMT2AALDH1A1DPP4FOLH1RAB9A
SCHEMBL21851699 0.80 CTBP2 (0.54) KMT2ACTBP2ALDH1A1MAPTSMN1; SMN2
SCHEMBL3286541 0.79 KMT2A (0.53) KMT2AMAPTSMN1; SMN2DPP4FOLH1
SCHEMBL3111571 0.78 KMT2A (0.56) KMT2AALDH1A1DPP4FOLH1RAB9A
SCHEMBL21851617 0.78 CTBP2 (0.45) CTBP2SMN1; SMN2HIF1A
SCHEMBL538512 0.77 KMT2A (0.60) KMT2ADPP4FOLH1RAB9A
SCHEMBL8209138 0.77 CTBP2 (0.54) KMT2ACTBP2ALDH1A1APAF1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3696155-B1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2022-06-29 EP disclosed
EP-3626708-B1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE PICKUP APPARATUS, ELECTRONIC APPARATUS, AND MOVING OBJECT CANON KK (JP) 2022-03-16 EP disclosed
US-20200377433-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-12-03 US disclosed
EP-3696155-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-08-19 EP disclosed
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-08-13 US disclosed
EP-3626708-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE PICKUP APPARATUS, ELECTRONIC APPARATUS, AND MOVING OBJECT CANON KABUSHIKI KAISHA (JP) 2020-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377433-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNL2, MCM4, CCNT1 KMT2A 2067/4885CTBP2 2481/4885ALDH1A1 367/4885
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNL2, MCM4, CCNT1 KMT2A 2067/4885CTBP2 2481/4885ALDH1A1 367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.