SCHEMBL538512

SCHEMBL538512

O=C(O)Cc1ccccc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.60
AKR1B1 P15121 2/20 0.59
PTGER1 P34995 2/20 0.56
PTGER4 P35408 2/20 0.56
PTGER3 P43115 2/20 0.56
PTGER2 P43116 2/20 0.56
PTGS1 P23219 2/20 0.56
DPP4 P27487 1/20 0.54
PTGS2 P35354 1/20 0.53
LMNA P02545 2/20 0.52
ABCC4 O15439 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
FOLH1 Q04609 1/20 0.51
ENPP2 Q13822 1/20 0.51
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP3 P08254 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27926479 0.98 KMT2A (0.58) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL28594606 0.98 KMT2A (0.58) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL27701716 0.98 KMT2A (0.58) KMT2AAKR1B1PTGER1PTGER4PTGER3
Hydrochloric Acid SCHEMBL11895689 0.98 KMT2A (0.58) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL29512995 0.98 KMT2A (0.58) KMT2AAKR1B1PTGER1PTGER4PTGER3
Ethane SCHEMBL28588588 0.96 PTGS1 (0.57) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL5961842 0.96 PTGS1 (0.59) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL8645744 0.94 PTGS1 (0.55) KMT2AAKR1B1PTGER1PTGER4PTGER3
SCHEMBL2925422 0.92 AKR1B1 (0.55) KMT2AAKR1B1PTGER1PTGER4PTGER3
Biphenyl SCHEMBL11146899 0.89 AKR1B1 (0.57) KMT2AAKR1B1PTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948166-A High-transparency polyamide resin and preparation method thereof 华峰集团有限公司 2023-10-27 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116621689-A L-lysine-biphenyl acetate, and preparation method and application thereof 山东省药学科学院 2023-08-22 CN claimed
CN-217119404-U Biphenylacetic acid purification device 河南羚锐生物药业有限公司 2022-08-05 CN claimed
CN-111574354-A Biphenylacetic acid and preparation method thereof 安徽鼎旺医药有限公司 2020-08-25 CN claimed
CN-109574809-B Synthesis method of hydroxyl-substituted phenanthrene derivative 华东理工大学 2020-07-03 CN claimed
CN-109574809-A A kind of synthetic method for the phenanthrene derivatives that hydroxyl replaces 华东理工大学 2019-04-05 CN claimed
CN-106431911-A Preparation and purification methods of 4-biphenylacetic acid 黄石市利福达医药化工有限公司 2017-02-22 CN claimed
CN-102993001-B Preparation of 4-biphenylacetic acid by palladium-catalyzed carbonylation UNIV TAIZHOU 2015-04-22 CN claimed
US-20150025020-A1 SELF-PRESERVED OIL DISPERSIONS COMPRISING BORIC ACID SANTEN SAS (FR) 2015-01-22 US claimed
CN-1657041-A Skin penetration absorption preparation QUAN YINGSHU (CN) 2005-08-24 CN claimed
CN-1640500-A Acrylic acid base adhesive composition, and its medicinal composition and transdermal treating system WANG SHUMING (CN) 2005-07-20 CN claimed
CN-1604950-A Glycerin triester plasticizer FERRO CORP (US) 2005-04-06 CN claimed
US-6156479-A Thermosetting anti-refective coatings BREWER SCIENCE, INC. (US) 2000-12-05 US claimed
WO-2000057247-A1 IMPROVED THERMOSETTING ANTI-REFLECTIVE COATINGS BREWER SCIENCE, INC. (US) 2000-09-28 WO claimed
CN-1042394-C Pharmaceutical composition containing felbinac AMERICAN CYANAMID CO (US) 1999-03-10 CN claimed
EP-0431080-A4 COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY 1992-10-21 EP claimed
EP-0431080-A1 COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) 1991-06-12 EP claimed
WO-1990002141-A1 COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) 1990-03-08 WO claimed
US-3991206-A Alleviation of eye inflammation by topical application of p-biphenylacetic acid AMERICAN CYANAMID COMPANY (US) 1976-11-09 US claimed