SCHEMBL2185187

SCHEMBL2185187

Cc1cccc(NCC(O)CS(=O)(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.45
HPGD P15428 2/20 0.42
GAA P10253 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
CASP6 P55212 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28234628 0.99 MAPT (0.47) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20502781 0.99 MAPT (0.47) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
Water SCHEMBL27900763 0.97 MAPT (0.46) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
Water SCHEMBL31674427 0.85 MAPT (0.45) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL21410669 0.84 HTT (0.37) MAPTCYP1A2CYP3A4HTTKDM4E
SCHEMBL5569666 0.83 MAPT (0.44) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL28303119 0.83 HTT (0.36) MAPTCYP1A2CYP3A4HTTKDM4E
SCHEMBL30504820 0.82 MTNR1A (0.49) MAPTHTTSMN1; SMN2HPGDGAA
SCHEMBL27762970 0.82 MTNR1A (0.49) MAPTHTTSMN1; SMN2HPGDGAA
SCHEMBL7902799 0.81 MAPT (0.53) MAPTHTTSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012168470-A1 METHOD FOR THE DETERMINATION OF THE CONCENTRATION OF VITAMIN B6 IN A SAMPLE BÜHLMANN LABORATORIES AG (CH) 2012-12-13 WO claimed
US-4877727-A Substrate for determining leucine aminopeptidase or gamma-glutamyltranspeptase activity KYOWA MEDEX CO., LTD. (JP) 1989-10-31 US claimed
EP-3722790-B1 COMPONENT MEASUREMENT SYSTEM, MEASUREMENT DEVICE, AND MEASUREMENT TIP TERUMO CORP (JP) 2023-08-09 EP disclosed
CN-112225808-A Human islet amyloid polypeptide (HIAPP) specific antibodies and uses thereof 生物控股有限公司 2021-01-15 CN disclosed
CN-104812774-B Human islet amyloid polypeptide (HIAPP) specific antibodies and uses thereof 生物控股有限公司 2020-11-06 CN disclosed
US-20200340888-A1 COMPONENT MEASUREMENT SYSTEM, MEASUREMENT DEVICE, AND MEASUREMENT TIP TERUMO KABUSHIKI KAISHA (JP) 2020-10-29 US disclosed
EP-3722790-A1 COMPONENT MEASUREMENT SYSTEM, MEASUREMENT DEVICE, AND MEASUREMENT TIP Terumo Kabushiki Kaisha (JP) 2020-10-14 EP disclosed
CN-111630375-A Component measurement system, measurement device, and measurement chip 泰尔茂株式会社 2020-09-04 CN disclosed
US-20190218528-A1 MODIFIED SARCOSINE OXIDASE, AND GENE AND PRODUCTION METHOD THEREFOR KIKKOMAN CORPORATION (JP) 2019-07-18 US disclosed
CN-109477837-A Method, composition and chip for detecting analyte in blood sample 泰尔茂株式会社 2019-03-15 CN disclosed
CN-107923838-A Biomaterial determining instrument 泰斯科有限公司 2018-04-17 CN disclosed
CN-1187590-C Sample collecting head TERUMO CORP (JP) 2005-02-02 CN disclosed
CN-1447104-A Liquid sample collector TERUMO CORP (JP) 2003-10-08 CN disclosed
CN-1104635-C Liquid Sample Collection Device TERUMO CORP (JP) 2003-04-02 CN disclosed
CN-1309769-A Analyzer ASAHI CHEMICAL IND (JP) 2001-08-22 CN disclosed
CN-1263260-A Sample collecting head TERUMO CORP (JP) 2000-08-16 CN disclosed
CN-1193106-A Liquid Sample Collection Device TERUMO CORP (JP) 1998-09-16 CN disclosed
EP-0152274-B1 METHOD FOR THE DETERMINATION OF LEUCINE AMINOPEPTIDASE (LAP) Kyowa Medex Co. Ltd. (JP) 1993-01-20 EP disclosed
US-4877727-A Substrate for determining leucine aminopeptidase or gamma-glutamyltranspeptase activity KYOWA MEDEX CO., LTD. (JP) 1989-10-31 US disclosed
EP-0152274-A2 Method for the determination of Leucine Aminopeptidase (LAP) Kyowa Medex Co. Ltd. (JP) 1985-08-21 EP disclosed