SCHEMBL2185189

SCHEMBL2185189

CCCCCCCCCCCCCCCCCCNC(=O)N1CC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.50
ASAH1 Q13510 3/20 0.47
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPK3 P27361 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SQOR Q9Y6N5 1/20 0.45
EPHX1 P07099 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185835 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2186377 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2185499 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2185405 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2184397 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2185069 1.00 NAMPT (0.50) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL2184763 0.92 EPHX2 (0.47) NAMPT
SCHEMBL17817102 0.76 FAAH (0.61) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL16653074 0.75 ASAH1 (0.44) NAMPTASAH1LMNACYP3A4CYP2D6
SCHEMBL10374083 0.75 NAMPT (0.49) NAMPTASAH1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343355-B1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2016-12-07 EP disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed