Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855732 | 0.86 | GSTP1 (0.43) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL29506065 | 0.86 | GSTP1 (0.43) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL29506185 | 0.85 | CXCR1 (0.42) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL18320494 | 0.85 | KMT2A (0.43) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL21855915 | 0.85 | CXCR1 (0.42) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL30660933 | 0.85 | KMT2A (0.43) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL29603922 | 0.78 | KMT2A (0.44) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL18320486 | 0.78 | KMT2A (0.44) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL22848181 | 0.77 | GSTP1 (0.40) | GSTP1GSTM2KMT2APRNPPOLB | |
| SCHEMBL18319841 | 0.76 | KMT2A (0.45) | GSTP1GSTM2KMT2APRNPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072656-A1 | IMIDOZOPYRIMIDINE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2020-04-09 | — | — | WO | disclosed |