SCHEMBL218535

SCHEMBL218535

CCCc1ccc2c(c1-c1cccc3ccccc13)[CH]c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.34
DHFR P00374 1/20 0.34
CTSG P08311 1/20 0.34
CNR1 P21554 2/20 0.34
KDM4E B2RXH2 3/20 0.33
ALOX15 P16050 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.33
CTSL P07711 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
TLR8 Q9NR97 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218825 0.89 KDM4E (0.36) DHFRKDM4EALOX15ALDH1A1GAA
SCHEMBL217922 0.83 ELANE (0.34) ELANECTSGKDM4EALDH1A1GAA
SCHEMBL218380 0.79 DHFR (0.44) DHFRKDM4EALDH1A1TSHRHSD17B10
SCHEMBL4723334 0.78 CNR1 (0.43) CNR1GAATSHRCNR2
SCHEMBL4767133 0.77 S1PR1 (0.46) DHFRALDH1A1TSHRHSD17B10
SCHEMBL4723465 0.77 GAA (0.45) CNR1GAACNR2CYP1A2CYP2C19
SCHEMBL219160 0.76 NR1H2 (0.34) ELANECTSGCTSLCTSSCTSK
SCHEMBL2687458 0.75 ELANE (0.33) ELANECTSGKDM4EALDH1A1GAA
SCHEMBL4721475 0.75 MAPT (0.50) DHFRKDM4EALDH1A1CNR2HPGD
SCHEMBL1029122 0.75 DNMT1 (0.41) DHFRKDM4EALDH1A1GAAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-20140066567-A1 Multiple Catalyst System for Olefin Polymerization and Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-03-06 US disclosed
US-8563647-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-22 US disclosed
EP-1620479-B1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2013-07-24 EP disclosed
EP-1558655-B1 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2012-08-29 EP disclosed
US-20120095157-A1 Multiple Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2012-04-19 US disclosed
US-8088867-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-01-03 US disclosed
US-8071687-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-06 US disclosed
EP-1753796-B1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2011-08-10 EP disclosed
US-7524910-B2 Polyolefin adhesive compositions and articles made therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-04-28 US disclosed
US-20090069475-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2009-03-12 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed