Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDXK | O00764 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656217 | 0.68 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL9656230 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL3679226 | 0.65 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL2260982 | 0.65 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL31184201 | 0.65 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Methane SCHEMBL6846367 | 0.63 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL15322103 | 0.63 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL26287526 | 0.63 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL11450620 | 0.62 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL11458019 | 0.62 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10PDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340907-A | Polymer conjugates comprising bioactive agents | 波利艾克蒂瓦有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-11787906-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2023-10-17 | — | — | US | disclosed |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2022-12-22 | — | — | US | disclosed |
| WO-2021051149-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2021-03-25 | — | — | WO | disclosed |
| US-20200123322-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2020-04-23 | — | — | US | disclosed |
| CN-110662561-A | Biodegradable drug-polymer conjugates | 波利艾克蒂瓦有限公司 | 2020-01-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123322-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | ADRB3, PTGER3, CHRNE | KDM4E 1790/4885ALDH1A1 1039/4885HPGD 881/4885 |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | PTGER1, PTGDR, F12 | KDM4E 2195/4885ALDH1A1 688/4885HPGD 422/4885 |
| US-11787906-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRM3 | KDM4E 1912/4885ALDH1A1 907/4885HPGD 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.