Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDXK | O00764 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656230 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL10943400 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL26649434 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL15322103 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL26287526 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| Methane SCHEMBL11010980 | 0.69 | PDXK (0.49) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL21853676 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL126039 | 0.67 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL3442719 | 0.67 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10PDXK | |
| SCHEMBL2260982 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517765-A1 | PREPARATIONS FOR MR DIAGNOSIS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-12-16 | — | — | EP | disclosed |
| WO-1991012822-A1 | PREPARATIONS FOR MR DIAGNOSIS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-09-05 | — | — | WO | disclosed |