Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133400 | 0.84 | FOLH1 (0.44) | FOLH1NOD1 | |
| SCHEMBL14300277 | 0.83 | FOLH1 (0.44) | FOLH1MMP2MMP8MMP12NOD1 | |
| SCHEMBL24618746 | 0.71 | BMP1 (0.51) | FOLH1MMP8BMP1 | |
| SCHEMBL20133399 | 0.71 | QRFPR (0.43) | FOLH1NOD1 | |
| SCHEMBL26440808 | 0.68 | FOLH1 (0.42) | FOLH1 | |
| SCHEMBL15295145 | 0.68 | FOLH1 (0.49) | FOLH1 | |
| SCHEMBL31429648 | 0.68 | SMN1; SMN2 (0.42) | FOLH1 | |
| SCHEMBL23636363 | 0.67 | CYP2C19 (0.45) | — | |
| SCHEMBL26504875 | 0.67 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL23790343 | 0.67 | FOLH1 (0.67) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200108159-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | WAKE FOREST UNIVERSITY | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200108159-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | MC1R, MC3R, MC5R | FOLH1 82/4885MMP2 4145/4885MMP8 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.