SCHEMBL21853699

SCHEMBL21853699

NC(C=O)/C=C/c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 3/20 0.46
TRPA1 O75762 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 2/20 0.46
HTR2A P28223 3/20 0.42
MAOB P27338 2/20 0.42
CYP2A6 P11509 1/20 0.42
CYP19A1 P11511 1/20 0.41
MAOA P21397 1/20 0.41
MAPT P10636 2/20 0.40
HDAC3 O15379 1/20 0.40
TNKS O95271 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28993553 0.86 MAOB (0.50) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL27543279 0.78 HTR2A (0.47) TRPA1CYP1A2HTR2AMAOBCYP19A1
SCHEMBL11075392 0.78 HTR2A (0.42) ALDH1A1LMNATRPA1ALOX5MAPK1
Lysine SCHEMBL23202422 0.78 GSR (0.53) CYP1A2GRIK1GRIK2
SCHEMBL2594007 0.77 ALDH1A1 (0.46) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL9960125 0.77 MAOB (0.50) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL29290527 0.74 ALDH1A1 (0.46) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL7289852 0.74 ALDH1A1 (0.46) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL155214 0.74 CYP1A2 (0.50) ALDH1A1LMNATRPA1ALOX5MAPK1
SCHEMBL13250871 0.74 ALDH1A1 (0.46) ALDH1A1LMNATRPA1ALOX5MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210235723-A1 APPLICATION OF CINNAMALDEHYDE AND/OR ALLANTOIN TO REPLACE HIGH ZINC AMOUNTS IN SUCKLING PIGLET FEED, FEED ADDITIVE OR ADDITIVE PREMIX, AND FEED HUNAN JINGTIAN TECHNOLOGY INDUSTRY CO., LTD. (CN) 2021-08-05 US disclosed
EP-3804529-A1 APPLICATION OF CINNAMALDEHYDE AND/OR ALLANTOIN TO REPLACE HIGH ZINC AMOUNTS IN SUCKLING PIGLET FEED, FEED ADDITIVE OR ADDITIVE PREMIX, AND FEED Hunan Jingtian Technology Industry Co., Ltd. (CN) 2021-04-14 EP disclosed
US-20200108159-A1 RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R WAKE FOREST UNIVERSITY 2020-04-09 US disclosed
CN-109180527-A The organogel compound and preparation method, organogel and application of a kind of pair of dimethylaminocinnamaldehyde derivative 信阳师范学院 2019-01-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200108159-A1 RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R MC1R, MC3R, MC5R ALDH1A1 1897/4885LMNA 4694/4885TRPA1 3644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.