SCHEMBL2185473

SCHEMBL2185473

CCCCCCCCCCCCCCCCCCP(=O)(O)OC(C)CCC

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.49
LPAR3 Q9UBY5 3/20 0.48
LPAR2 Q9HBW0 1/20 0.48
S1PR2 O95136 5/20 0.46
S1PR1 P21453 5/20 0.46
S1PR3 Q99500 5/20 0.46
S1PR4 O95977 4/20 0.46
TRPM8 Q7Z2W7 4/20 0.46
FDPS P14324 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976301 1.00 SMPD1 (0.49) SMPD1LPAR3LPAR2S1PR2S1PR1
SCHEMBL10799957 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL11649168 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL16427895 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL14890431 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL2150294 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL2184552 0.87 LPAR3 (0.50) SMPD1LPAR3LPAR2TRPM8
SCHEMBL1065489 0.86 SMPD1 (0.53) SMPD1LPAR3LPAR2S1PR2S1PR1
SCHEMBL28389138 0.85 METAP1 (0.44) SMPD1S1PR2S1PR1S1PR3S1PR4
SCHEMBL2189539 0.83 LPAR3 (0.54) SMPD1LPAR3LPAR2TRPM8FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343355-B1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2016-12-07 EP disclosed
EP-1686167-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2016-05-25 EP disclosed
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed