Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185473 | 1.00 | SMPD1 (0.49) | SMPD1LPAR3LPAR2S1PR2S1PR1 | |
| SCHEMBL10799957 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL11649168 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL16427895 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL14890431 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL2150294 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL2184552 | 0.87 | LPAR3 (0.50) | SMPD1LPAR3LPAR2TRPM8 | |
| SCHEMBL1065489 | 0.86 | SMPD1 (0.53) | SMPD1LPAR3LPAR2S1PR2S1PR1 | |
| SCHEMBL28389138 | 0.85 | METAP1 (0.44) | SMPD1S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL2189539 | 0.83 | LPAR3 (0.54) | SMPD1LPAR3LPAR2TRPM8FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840194-B1 | Gear fluids | AFTON CHEMICAL CORP (US) | 2009-05-13 | — | — | EP | claimed |
| US-7410935-B2 | Gear fluids | AFTON CHEMICAL CORPORATION (US) | 2008-08-12 | — | — | US | claimed |
| EP-1840194-A1 | Gear fluids | Afton Chemical Corporation (US) | 2007-10-03 | — | — | EP | claimed |
| US-20070225182-A1 | Gear fluids | AFTON CHEMICAL CORPORATION | 2007-09-27 | — | — | US | claimed |
| EP-1577370-A2 | Power transmission fluids | Afton Chemical Corporation (US) | 2005-09-21 | — | — | EP | claimed |
| US-20050202979-A1 | Power transmission fluids with enhanced extreme pressure characteristics | ETHYL PETROLEUM ADDITIVES, INC. | 2005-09-15 | — | — | US | claimed |
| EP-1840194-B1 | Gear fluids | AFTON CHEMICAL CORP (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1840194-A1 | Gear fluids | Afton Chemical Corporation (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1577370-A2 | Power transmission fluids | Afton Chemical Corporation (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20050202979-A1 | Power transmission fluids with enhanced extreme pressure characteristics | ETHYL PETROLEUM ADDITIVES, INC. | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225182-A1 | Gear fluids | PHOSPHO1, F12, PIK3CA | SMPD1 3456/4885LPAR3 63/4885LPAR2 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.