SCHEMBL2185478

SCHEMBL2185478

Oc1[c]c(O)ncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12076717 0.74
SCHEMBL12076718 0.74
SCHEMBL128334 0.59
SCHEMBL672185 0.57
SCHEMBL1071219 0.57 CCR1 (0.48)
SCHEMBL5586604 0.57
SCHEMBL788891 0.56
SCHEMBL3573509 0.56
SCHEMBL3234401 0.55 TSHR (0.50)
SCHEMBL9779787 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2065057-A2 Chelating conjugates having a substituted aromatic moiety and derivatives thereof Mallinckrodt Inc. (US) 2009-06-03 EP claimed
US-20090053137-A1 Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof SpecGx LLC 2009-02-26 US claimed
EP-1993613-A2 CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF Mallinckrodt, Inc. (US) 2008-11-26 EP claimed
WO-2007106544-A2 CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF MALLINCKRODT INC. (US) 2007-09-20 WO claimed
US-9217009-B2 Version of FDG detectable by single-photon emission computed tomography MALLINCKRODT LLC (US) 2015-12-22 US disclosed
US-20140378677-A1 VERSION OF FDG DETECTABLE BY SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY MALLINCKRODT VETERINARY, INC. 2014-12-25 US disclosed
US-8858916-B2 Metal chelate linked to a hexose carrier for use as a metallopharmaceutical diagnostic or therapeutic agent MALLINCKRODT LLC (US) 2014-10-14 US disclosed
US-20110177004-A1 Version of FDG Detectable by Single-Photon Emission Computed Tomography OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.) 2011-07-21 US disclosed
EP-2341944-A2 CONJUGATES OF HEXOSE AND METAL COORDINATING COMPOUNDS FOR IMAGING PURPOSES Mallinckrodt Inc. (US) 2011-07-13 EP disclosed
WO-2010039609-A2 A VERSION OF FDG DETECTABLE BY SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY MALLINCKRODT INC. (US) 2010-04-08 WO disclosed
EP-2065057-A3 Chelating conjugates having a substituted aromatic moiety and derivatives thereof Mallinckrodt Inc. (US) 2009-08-12 EP disclosed
EP-2065057-A2 Chelating conjugates having a substituted aromatic moiety and derivatives thereof Mallinckrodt Inc. (US) 2009-06-03 EP disclosed
EP-2065057-A2 Chelating conjugates having a substituted aromatic moiety and derivatives thereof Mallinckrodt Inc. (US) 2009-06-03 EP disclosed
US-20090053137-A1 Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof SpecGx LLC 2009-02-26 US disclosed
EP-1993613-A2 CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF Mallinckrodt, Inc. (US) 2008-11-26 EP disclosed
WO-2007106544-A2 CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF MALLINCKRODT INC. (US) 2007-09-20 WO disclosed