Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 13/20 | 0.79 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.72 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.72 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.72 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.72 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.72 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.72 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.60 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.60 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723593 | 0.88 | WNT3A (1.00) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2182327 | 0.88 | WNT3A (1.00) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2182842 | 0.87 | WNT3A (0.93) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27971532 | 0.87 | WNT3A (0.93) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1492812 | 0.84 | MAPK1 (0.62) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2184822 | 0.84 | WNT3A (0.83) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2185259 | 0.83 | WNT3A (0.77) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2184953 | 0.83 | WNT3A (0.73) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2185279 | 0.83 | WNT3A (0.77) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2184045 | 0.83 | WNT3A (0.80) | WNT3APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166132-A1 | Gamma Secretase Modulators | AMGEN INC. (US) | 2011-07-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166132-A1 | Gamma Secretase Modulators | BACE1, BACE2, PSEN1 | WNT3A 1903/4885PSEN1 3/4885PSEN2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.