Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | GRM8 | O00222 | 1/20 | 0.62 |
| ▸ | GRM6 | O15303 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.62 |
| ▸ | GSR | P00390 | 1/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.62 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL11697693 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL9241674 | 0.98 | GRM8 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL8987898 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL3499202 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL9646845 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL10824535 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL4025166 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL718336 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL8746869 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1782280 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4710916-A1 | COMPOSITION COMPRISING GLUTAMATE FOR CARIES PREVENTION | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) (ES) | 2026-03-18 | — | — | EP | claimed |
| EP-4259092-B1 | PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR TOPICAL USE COMPRISING A POLYMER IN THE FORM OF A PULVERULENT SOLID AS THICKENING AGENT | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2026-02-18 | — | — | EP | claimed |
| EP-4666864-A1 | METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING FOOD | AJINOMOTO CO., INC. (JP) | 2025-12-24 | — | — | EP | claimed |
| EP-4666868-A1 | METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING LIQUID FOOD | AJINOMOTO CO., INC. (JP) | 2025-12-24 | — | — | EP | claimed |
| US-20250366492-A1 | METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING FOOD | AJINOMOTO CO., INC. (JP) | 2025-12-04 | — | — | US | claimed |
| US-20250366493-A1 | METHOD FOR PRODUCING MODIFIED PROTEIN-CONTAINING LIQUID FOOD | AJINOMOTO CO., INC. (JP) | 2025-12-04 | — | — | US | claimed |
| EP-4608985-A1 | CELL-FREE PROTEIN SYNTHESIS SYSTEMS, REACTION MIXTURES FOR SAME, AND METHODS FOR PREPARING PROTEINS | Sanofi Pasteur Limited (CA) | 2025-09-03 | — | — | EP | claimed |
| CN-119592598-A | Application of controllable delivery of substances among multiple membraneless compartments in cell-free system | 上海交通大学 | 2025-03-11 | — | — | CN | claimed |
| WO-2004004754-A1 | NOVEL MEDICAMENT COMBINATIONS BASED ON MAGNESIUM SALTS AND FIBRINOLYTICS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-01-15 | — | — | WO | claimed |
| US-20030113408-A1 | Carbonated fortified milk-based beverage and method for suppressing bacterial growth in the beverage | PARSONS, RONALD O. | 2003-06-19 | — | — | US | claimed |
| US-6500450-B1 | Composition for treating migraine headaches | AKESO HEALTH SCIENCES, LLC | 2002-12-31 | — | — | US | claimed |
| US-6403129-B1 | WATER; NONFAT DRY MILK; CALCIUM, MAGNESIUM AND POTASSIUM SALTS; | MAC FARMS, INC. | 2002-06-11 | — | — | US | claimed |
| EP-1051086-B1 | DIETETIC COMPOSITION IN THE FORM OF A SUBSTITUTION SALT FOR TABLE SALT | SANOFI SYNTHELABO (FR) | 2002-04-17 | — | — | EP | claimed |
| US-5851419-A | Metal corrosion inhibitive coolant composition containing alkenylsuccinic acid or alkali metal salt thereof | CCI CO., LTD. (JP) | 1998-12-22 | — | — | US | claimed |
| EP-0820771-A2 | Pharmaceutical compositions for the treatment of neuropathies containing a lipid-soluble thiamine and a magnesium compound | WÖRWAG PHARMA GmbH (DE) | 1998-01-28 | — | — | EP | claimed |
| EP-0530220-B1 | PHARMACEUTICAL COMPOSITION | S & V ENGINEERING KFT (HU) | 1997-09-03 | — | — | EP | claimed |
| EP-0183736-B1 | SALT MIXTURE HAVING A LOW SODIUM CONTENT, USED AS SUBSTITUTE FOR COOKING SALT | Diamalt GmbH (DE) | 1990-07-18 | — | — | EP | claimed |
| US-4016301-A | Electrically conductible gellable composition with ionized salt | LECTROFOOD, INC. (US) | 1977-04-05 | — | — | US | claimed |