Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21857984 | 0.85 | CA9 (0.42) | CA9CA12CA3CA4CA6 | |
| SCHEMBL21857932 | 0.79 | CA12 (0.41) | CA9CA12CA3CA4CA6 | |
| SCHEMBL30950399 | 0.78 | TTR (0.56) | CA9CA12CA3CA4CA6 | |
| SCHEMBL8514648 | 0.78 | TTR (0.56) | CA9CA12CA3CA4CA6 | |
| SCHEMBL29018091 | 0.77 | CA12 (0.47) | CA9CA12CA3CA4CA6 | |
| SCHEMBL30461559 | 0.77 | CA12 (0.47) | CA9CA12CA3CA4CA6 | |
| SCHEMBL1458540 | 0.75 | CA1 (0.43) | CA9CA12CA4CA6CA5A | |
| SCHEMBL9635973 | 0.71 | KMT2A (0.47) | ALDH1A1HSD17B10TSHRCDK2CYP3A4 | |
| SCHEMBL21857967 | 0.70 | TTR (0.54) | CA9CA12CA3CA4CA6 | |
| SCHEMBL30842291 | 0.69 | CA12 (0.56) | CA9CA12CA3CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-09-03 | — | — | US | claimed |
| WO-2020081852-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-04-23 | — | — | WO | claimed |
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | PPP5C, MTMR1, PPM1G | CA9 4553/4885CA12 4768/4885CA3 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.