Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514648 | 0.91 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL30950399 | 0.91 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21725437 | 0.80 | TTR (0.60) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL27459951 | 0.79 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9489907 | 0.79 | CYP3A4 (0.48) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10882233 | 0.79 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL3036841 | 0.79 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10478980 | 0.79 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29018091 | 0.75 | CA12 (0.47) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL30461559 | 0.75 | CA12 (0.47) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-09-03 | — | — | US | claimed |
| WO-2020081852-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-04-23 | — | — | WO | claimed |
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277256-A1 | SELECTIVE SHIP INHIBITORS FOR TREATING DISEASE | PPP5C, MTMR1, PPM1G | TTR 1675/4885FABP4 1510/4885CCNA2 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.