Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611540 | 0.93 | MAPT (0.49) | ALDH1A1MAPTLMNAPIN1MERTK | |
| SCHEMBL21611436 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAPIN1SMN1; SMN2 | |
| SCHEMBL21611426 | 0.84 | MAPT (0.56) | ALDH1A1MAPTLMNAPIN1SMN1; SMN2 | |
| SCHEMBL21611475 | 0.83 | MAPT (0.56) | ALDH1A1MAPTLMNAPIN1MERTK | |
| SCHEMBL21611500 | 0.82 | MAPT (0.60) | ALDH1A1MAPTLMNAPIN1SMN1; SMN2 | |
| SCHEMBL21611406 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAPIN1SMN1; SMN2 | |
| SCHEMBL9165003 | 0.79 | CA1 (0.49) | ALDH1A1MAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL21611509 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPIN1MERTK | |
| SCHEMBL21858751 | 0.77 | MAPT (0.55) | ALDH1A1MAPTLMNAPIN1SMN1; SMN2 | |
| SCHEMBL21858753 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAPIN1MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113038990-A | Novel amino-pyrimidinone-piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-06-25 | — | — | CN | disclosed |
| WO-2020079205-A1 | NEW AMINO-PYRIMIDONYL-PIPERIDINYL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2020-04-23 | — | — | WO | disclosed |