Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21859001 | 1.00 | CYP2C9 (0.41) | CYP2C9CASP1ALDH1A1NPSR1LMNA | |
| SCHEMBL3289090 | 0.82 | NPSR1 (0.40) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL29980176 | 0.82 | NPSR1 (0.45) | CYP2C9ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL3289092 | 0.82 | NPSR1 (0.40) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL4161766 | 0.82 | NPSR1 (0.40) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL19987092 | 0.82 | NPSR1 (0.45) | CYP2C9ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL21174039 | 0.82 | NPSR1 (0.45) | CYP2C9ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL13756506 | 0.81 | KEAP1 (0.44) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL9562369 | 0.81 | KEAP1 (0.44) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL31696352 | 0.81 | KEAP1 (0.44) | CYP2C9ALDH1A1NPSR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214998-A1 | CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF | BIONOMICS LTD (AU) | 2025-07-03 | — | — | US | disclosed |
| US-12275732-B2 | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof | BIONOMICS LIMITED (AU) | 2025-04-15 | — | — | US | disclosed |
| EP-3867252-B1 | 6-INDAN-2-YLOXY-3-(MORPHOLINE-4-CARBONYL)-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES AND SIMILAR COMPOUNDS AS MODULATORS OF THE ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR FOR THE TREATMENT OF ANXIETY | BIONOMICS LTD (AU) | 2023-12-06 | — | — | EP | disclosed |
| US-20210355124-A1 | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof | BIONOMICS LIMITED (AU) | 2021-11-18 | — | — | US | disclosed |
| US-20210355124-A1 | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof | BIONOMICS LIMITED (AU) | 2021-11-18 | — | — | US | disclosed |
| WO-2020077414-A1 | CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214998-A1 | CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF | CHRNA7, CHRNA5, CHRNA1 | CYP2C9 1995/4885CASP1 4454/4885ALDH1A1 836/4885 |
| US-12275732-B2 | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof | CHRNA7, CHRNA1, CHRNA5 | CYP2C9 1938/4885CASP1 4402/4885ALDH1A1 832/4885 |
| US-20210355124-A1 | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof | CHRNA7, CHRNA1, CHRNA5 | CYP2C9 1938/4885CASP1 4402/4885ALDH1A1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.