Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399987 | 0.93 | TRPA1 (0.83) | TRPA1 | |
| SCHEMBL19399960 | 0.91 | TRPA1 (0.83) | TRPA1 | |
| SCHEMBL17609654 | 0.91 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL19399970 | 0.91 | TRPA1 (0.69) | TRPA1 | |
| SCHEMBL21609651 | 0.90 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL21609629 | 0.90 | TRPA1 (0.82) | TRPA1 | |
| SCHEMBL21527540 | 0.89 | TRPA1 (0.83) | TRPA1 | |
| SCHEMBL17609682 | 0.89 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL19396185 | 0.89 | TRPA1 (0.92) | TRPA1 | |
| SCHEMBL19399904 | 0.88 | TRPA1 (0.84) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |