SCHEMBL21861622

SCHEMBL21861622

CN/C(=C\SC)NC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
TAS2R38 P59533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18633910 0.75
SCHEMBL12844895 0.71
SCHEMBL14724921 0.67 CRBN (0.32) CRBNTAS2R38
SCHEMBL24782396 0.64 CRBN (0.30) CRBN
SCHEMBL17383156 0.64
Diacetamide SCHEMBL97089 0.61
SCHEMBL18510170 0.61
SCHEMBL4397 0.61
SCHEMBL2401765 0.61 KDM4E (0.54) CRBNTAS2R38
SCHEMBL20411614 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193880-B1 INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL LILLY CO ELI (US) 2020-03-25 EP disclosed