Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972351 | 0.73 | MGLL (0.42) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL11457779 | 0.73 | MGLL (0.42) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL3683381 | 0.73 | GSK3A (0.32) | MGLLGSK3AGSK3B | |
| SCHEMBL9460127 | 0.69 | MGLL (0.35) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL3443427 | 0.69 | DNMT1 (0.36) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL28568487 | 0.69 | MGLL (0.38) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL43978 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL708908 | 0.69 | MGLL (0.38) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL18389677 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL29017 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056192-A1 | ANTIBODY CONJUGATES OF TOLL-LIKE RECEPTOR AGONISTS | SILVERBACK THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |