SCHEMBL21862736

SCHEMBL21862736

c1ccc(-c2ccc(-c3cc(-c4ccc5ccccc5c4)nc(-c4cccc5oc6cc(-n7c8ccccc8c8c9ccccc9ccc87)ccc6c45)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
PIM1 P11309 1/20 0.33
FLT3 P36888 3/20 0.32
BMX P51813 2/20 0.32
ALDH1A1 P00352 3/20 0.31
MAPT P10636 3/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
PTGES O14684 2/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25975621 0.93 PIM1 (0.33) CYP1A1CYP1B1PIM1FLT3BMX
SCHEMBL23740336 0.93 ALDH1A1 (0.32) CYP1A1ALDH1A1MAPTKDM4EHPGD
SCHEMBL21862739 0.92 CYP1A1 (0.35) CYP1A1CYP1B1PIM1FLT3ALDH1A1
SCHEMBL23740478 0.92 ALDH1A1 (0.32) CYP1A1ALDH1A1MAPTKDM4EHPGD
SCHEMBL21671385 0.91 CYP1A1 (0.34) CYP1A1CYP1B1PIM1ALDH1A1MAPT
SCHEMBL23740731 0.91 TDP1 (0.32) CYP1A1CYP1B1PIM1ALDH1A1MAPT
SCHEMBL23740652 0.90 TDP1 (0.33) CYP1A1ALDH1A1MAPTKDM4EHPGD
SCHEMBL26415895 0.90 MAPT (0.36) CYP1A1ALDH1A1MAPTKDM4EHPGD
SCHEMBL21862721 0.89 ALDH1A1 (0.32) ALDH1A1MAPTKDM4EHPGDCYP1A2
SCHEMBL23740338 0.89 ALDH1A1 (0.32) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020071778-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DIODE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT EMITTING DIODE 엘티소재주식회사 2020-04-09 WO disclosed