Trientine

Trientine

SCHEMBL2186312

CCN(CC)CCN(CC)CC.NCCNCCNCCN

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.55
CA6 P23280 5/20 0.55
CA7 P43166 5/20 0.55
CA9 Q16790 5/20 0.55
CA14 Q9ULX7 5/20 0.55
CA5B Q9Y2D0 5/20 0.55
CA2 P00918 4/20 0.55
CA4 P22748 4/20 0.55
CA5A P35218 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
LMNA P02545 3/20 0.55
CA3 P07451 3/20 0.55
ALOX15 P16050 3/20 0.55
CA1 P00915 2/20 0.55
ALDH1A1 P00352 2/20 0.55
TP53 P04637 1/20 0.55
KDM4E B2RXH2 1/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2C9 P11712 2/20 0.52
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11871853 0.93 CYP2C19 (0.56) CA12CA6CA7CA9CA14
SCHEMBL30607521 0.93 CYP2C19 (0.56) CA12CA6CA7CA9CA14
Trientine SCHEMBL8987400 0.91 CA12 (0.50) CA12CA6CA7CA9CA14
SCHEMBL323463 0.90 CYP2C19 (0.58) CA12CA6CA7CA9CA14
SCHEMBL4562850 0.88 PAOX (0.53) CA12CA6CA7CA9CA14
SCHEMBL28327427 0.87 CA12 (0.59) CA12CA6CA7CA9CA14
SCHEMBL15746957 0.87 CYP2C19 (0.50) CA12CA6CA7CA9CA14
SCHEMBL10123951 0.85 CYP2C19 (0.58) CA12CA6CA7CA9CA14
SCHEMBL14451145 0.85 CYP2C19 (0.48) CA12CA6CA7CA9CA14
SCHEMBL10123895 0.84 CYP2C19 (0.52) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192239-A1 ANTI-MICROBIAL COMPOSITION Byotrol PLC (GB) 2023-06-14 EP disclosed
EP-2797413-B1 ANTI-MICROBIAL COMPOSITION BYOTROL PLC (GB) 2018-09-12 EP disclosed
US-9814688-B2 Antimicrobial compositions and methods for their use DERMCARE-VET PTY LTD (AU) 2017-11-14 US disclosed
US-20170165208-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE DERMCARE-VET PTY LTD (AU) 2017-06-15 US disclosed
US-9555015-B2 Antimicrobial compositions and methods for their use DERMCARE-VET PTY LTD (AU) 2017-01-31 US disclosed
EP-2797413-A1 ANTI-MICROBIAL COMPOSITION Byotrol PLC (GB) 2014-11-05 EP disclosed
WO-2013098547-A1 ANTI-MICROBIAL COMPOSITION BYOTROL PLC (GB) 2013-07-04 WO disclosed
EP-1755576-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE DERMCARE VET PTY LTD (AU) 2011-07-13 EP disclosed
EP-1755576-A4 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE DERMCARE VET PTY LTD (AU) 2009-07-08 EP disclosed
US-20070282008-A1 Antimicrobial Compositions and Methods for Their Use DEMCARE-VET PTY LTD (AU) 2007-12-06 US disclosed
EP-1755576-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE DERMCARE-VET PTY LTD (AU) 2007-02-28 EP disclosed
WO-2005097094-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE DERMCARE-VET PTY LTD (AU) 2005-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170165208-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR THEIR USE CUTA, PUF60, UNG CA12 965/4885CA6 467/4885CA7 199/4885
US-20070282008-A1 Antimicrobial Compositions and Methods for Their Use CUTA, PUF60, UNG CA12 965/4885CA6 467/4885CA7 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.