Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 4/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537028 | 0.77 | TNF (0.63) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL30260939 | 0.77 | TNF (0.63) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL31677511 | 0.76 | TNF (0.61) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL30548032 | 0.74 | TNF (0.59) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL30548029 | 0.74 | TNF (0.59) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL4048611 | 0.74 | TNF (1.00) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL6500542 | 0.74 | TNF (0.59) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL1420260 | 0.74 | TNF (0.59) | TNFRIPK1GPR84AHRCMA1 | |
| SCHEMBL24953856 | 0.74 | TNF (0.39) | TNFRIPK1AHRBRD4TAF1 | |
| SCHEMBL1374474 | 0.72 | TNF (0.54) | TNFRIPK1GPR84AHRCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |