Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 5/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TAF1 | P21675 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591462 | 1.00 | TNF (0.54) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL23058908 | 0.84 | TNF (0.48) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL28736127 | 0.78 | MAPT (0.46) | TNFRIPK1AHRPIM3PDPK1 | |
| SCHEMBL29591846 | 0.78 | MAPT (0.46) | TNFRIPK1AHRPIM3PDPK1 | |
| SCHEMBL10594346 | 0.78 | TNF (0.43) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL4417261 | 0.76 | PIM3 (0.41) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL4424876 | 0.76 | PIM3 (0.41) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL4419322 | 0.76 | PIM3 (0.41) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL15741308 | 0.76 | TNF (0.42) | TNFRIPK1AHRPIM3BRD4 | |
| SCHEMBL1875458 | 0.76 | TNF (0.42) | TNFRIPK1AHRPIM3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | claimed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | claimed |
| US-11780846-B2 | Compound, organic electroluminescent device including the same and electronic apparatus | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
| US-11780846-B2 | Compound, organic electroluminescent device including the same and electronic apparatus | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
| US-20220105066-A1 | Antidotes to Cyanide Poisoning | THE GENERAL HOSPITAL CORPORATION | 2022-04-07 | — | — | US | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| US-20200283448-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-10411203-B2 | Organic electroluminescent element, and lighting device and display device each using same | Konica Minolta, Inc. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20160336522-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHTING DEVICE AND DISPLAY DEVICE EACH USING SAME | Konica Minolta, Inc. (JP) | 2016-11-17 | — | — | US | disclosed |
| US-20160336522-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHTING DEVICE AND DISPLAY DEVICE EACH USING SAME | Konica Minolta, Inc. (JP) | 2016-11-17 | — | — | US | disclosed |
| US-9356243-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-05-31 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | WELLA OPERATIONS US, LLC | 2008-06-12 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351266-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1720615-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005087187-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050193504-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | TNF 3353/4885RIPK1 3512/4885AHR 988/4885 |
| US-20080134450-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, KRTCAP2 | TNF 3353/4885RIPK1 3512/4885AHR 988/4885 |
| US-20200283448-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS | GJB2, SLC7A5, GJA1 | TNF 1626/4885RIPK1 1464/4885AHR 2698/4885 |
| US-11780846-B2 | Compound, organic electroluminescent device including the same and electronic apparatus | GJB2, SLC7A5, GJA1 | TNF 1626/4885RIPK1 1464/4885AHR 2698/4885 |
| US-20220105066-A1 | Antidotes to Cyanide Poisoning | OAT, CAT, ABCB7 | TNF 4565/4885RIPK1 2551/4885AHR 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.