Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 6/20 | 0.39 |
| ▸ | JAK3 | P52333 | 6/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741027 | 0.80 | SMPD3 (0.50) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL545331 | 0.80 | PIK3CG (0.61) | PIK3CGSMPD3AXLJAK2JAK3 | |
| Ammonia Solution, Strong SCHEMBL14158423 | 0.78 | PIK3CG (0.59) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL16629030 | 0.77 | PIK3CG (0.57) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL31725153 | 0.77 | PIK3CG (0.57) | PIK3CGSMPD3AXLHTR6PDE2A | |
| SCHEMBL15308491 | 0.77 | PIK3CG (0.49) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL7851573 | 0.77 | SMPD3 (0.47) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL13772943 | 0.77 | PIK3CG (0.57) | PIK3CGSMPD3AXLHTR6PDE2A | |
| SCHEMBL38666729 | 0.77 | SMPD3 (0.43) | PIK3CGSMPD3AXLJAK2JAK3 | |
| SCHEMBL7453195 | 0.77 | SMPD3 (0.43) | PIK3CGSMPD3AXLJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |