SCHEMBL21864136

SCHEMBL21864136

CCCCCc1cc(OC)c(CC=C(C)C)c(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 4/20 0.58
▸ PPARA Q07869 3/20 0.58
▸ PPARD Q03181 2/20 0.58
▸ CYP19A1 P11511 1/20 0.55
▸ CNR2 P34972 3/20 0.52
▸ CNR1 P21554 2/20 0.52
▸ TRPV1 Q8NER1 2/20 0.52
▸ OPRM1 P35372 2/20 0.52
▸ TRPA1 O75762 1/20 0.52
▸ INHA P05111 1/20 0.52
▸ SLC6A2 P23975 1/20 0.52
▸ HTR2A P28223 1/20 0.52
▸ SLC6A4 P31645 1/20 0.52
▸ SLC6A3 Q01959 1/20 0.52
▸ KCNH2 Q12809 1/20 0.52
▸ TRPM8 Q7Z2W7 1/20 0.52
▸ TRPV3 Q8NET8 1/20 0.52
▸ TRPV4 Q9HBA0 1/20 0.52
▸ TRPV2 Q9Y5S1 1/20 0.52
▸ PTGS2 P35354 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8702072 0.89 PPARG (0.49) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25341432 0.88 PPARG (0.71) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL21864132 0.88 PPARG (0.71) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25342653 0.87 PPARG (0.70) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25342650 0.87 PPARG (0.70) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25341797 0.81 PPARG (0.80) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL29855454 0.81 PPARG (0.80) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL13214110 0.81 PPARG (0.80) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25341073 0.80 PPARG (0.78) PPARGPPARAPPARDCYP19A1CNR2
SCHEMBL25341069 0.80 PPARG (0.78) PPARGPPARAPPARDCYP19A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210276936-A1 Synthesis of Cannabigerol TREEHOUSE BIOTECH, INC. 2021-09-09 — — US disclosed
US-11040932-B2 Synthesis of cannabigerol TREEHOUSE BIOTECH, INC. (US) 2021-06-22 — — US disclosed
US-20200115306-A1 SYNTHESIS OF CANNABIGEROL TREEHOUSE BIOTECH, INC. 2020-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115306-A1 SYNTHESIS OF CANNABIGEROL COASY, ACSL3, SQLE PPARG 441/4885PPARA 395/4885PPARD 521/4885
US-11040932-B2 Synthesis of cannabigerol COASY, ACSL3, SQLE PPARG 441/4885PPARA 395/4885PPARD 521/4885
US-20210276936-A1 Synthesis of Cannabigerol COASY, ACSL3, SQLE PPARG 441/4885PPARA 395/4885PPARD 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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