Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864681 | 0.77 | FFAR1 (0.41) | CHEK2 | |
| SCHEMBL1664049 | 0.73 | USP2 (0.57) | HRH3LIPG | |
| SCHEMBL21697492 | 0.72 | PARP14 (0.39) | HRH3GPR119CHEK2ADRA2AADRA2B | |
| SCHEMBL21864603 | 0.71 | HTR1D (0.46) | — | |
| SCHEMBL17888639 | 0.71 | PARP14 (0.38) | HRH3GPR119CHEK2LIPGADRA2A | |
| SCHEMBL23190760 | 0.71 | MAPT (0.46) | — | |
| SCHEMBL21864622 | 0.71 | MAPT (0.38) | HRH3LIPG | |
| SCHEMBL1318684 | 0.70 | CDK8 (0.44) | HRH3CHEK2LIPG | |
| SCHEMBL17899367 | 0.70 | MAPT (0.48) | CHEK2 | |
| SCHEMBL17899403 | 0.70 | PARP14 (0.37) | HRH3GPR119CHEK2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020071550-A1 | CDK8 INHIBITOR AND USE OF SAME | 京都薬品工業株式会社 | 2020-04-09 | — | — | WO | disclosed |