Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864624 | 0.78 | HTR1D (0.38) | HTR1BHTR1AHTR1D | |
| SCHEMBL21864683 | 0.71 | HRH3 (0.38) | LIPGHRH3 | |
| SCHEMBL21864684 | 0.71 | CHEK2 (0.41) | — | |
| SCHEMBL12115089 | 0.69 | CDK8 (0.41) | MAPTPOLBTP53CTPS1LIPG | |
| SCHEMBL1320572 | 0.68 | CDK8 (0.45) | MAPTPOLBTP53HTR1BCTPS1 | |
| SCHEMBL12115165 | 0.66 | HRH3 (0.38) | HRH3 | |
| SCHEMBL12115091 | 0.66 | CDK8 (0.41) | MAPTPOLBTP53CTPS1LIPG | |
| SCHEMBL21864603 | 0.66 | HTR1D (0.46) | HTR1BHTR1AHTR1D | |
| SCHEMBL21864582 | 0.66 | MTNR1B (0.39) | MAPTPOLBTP53HTR1BCTPS1 | |
| SCHEMBL1318684 | 0.64 | CDK8 (0.44) | MAPTPOLBTP53HTR1BCTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020071550-A1 | CDK8 INHIBITOR AND USE OF SAME | 京都薬品工業株式会社 | 2020-04-09 | — | — | WO | disclosed |