SCHEMBL2186533

SCHEMBL2186533

O=C(CCC(=O)NCCO)NCCO

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
ALDH1A1 P00352 4/20 0.50
CNR1 P21554 4/20 0.50
LMNA P02545 1/20 0.48
NAAA Q02083 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
USP2 O75604 1/20 0.48
MAPT P10636 1/20 0.48
CNR2 P34972 2/20 0.46
TRPV1 Q8NER1 2/20 0.46
SELP P16109 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
FAAH O00519 1/20 0.46
KCNK3 O14649 1/20 0.46
BLM P54132 1/20 0.46
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622441 0.91
SCHEMBL2484600 0.89 PHF8 (0.50) GAAALDH1A1CNR1LMNAKMT2A
SCHEMBL7144946 0.89 GAA (0.47) GAAALDH1A1CNR1LMNANAAA
SCHEMBL8896628 0.88 CNR1 (0.53) ALDH1A1CNR1NAAAMEN1KMT2A
SCHEMBL4103969 0.88 SELP (0.56) ALDH1A1CNR1NAAAMEN1KMT2A
SCHEMBL8412393 0.87 HDAC3 (0.52) GAAALDH1A1CNR1LMNANAAA
SCHEMBL1230303 0.87 GAA (0.46) GAAALDH1A1CNR1LMNANAAA
SCHEMBL21706813 0.87 GAA (0.55) GAAALDH1A1CNR1LMNANAAA
SCHEMBL21216091 0.86 SELP (0.59) ALDH1A1CNR1NAAAMEN1KMT2A
SCHEMBL21505016 0.86 CNR1 (0.46) GAAALDH1A1CNR1LMNANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200165498-A1 LAMINATING ADHESIVES BASED ON PRIMARY HYDROXYL-CONTAINING CURATIVES HENKEL AG & CO. KGAA (DE) 2020-05-28 US disclosed
EP-1809475-B1 LAMINATING ADHESIVES BASED ON PRIMARY HYDROXYL-CONTAINING CURATIVES Henkel IP & Holding GmbH (DE) 2018-01-10 EP disclosed
US-20170166790-A1 LAMINATING ADHESIVES BASED ON PRIMARY HYDROXYL-CONTAINING CURATIVES HENKEL CORPORATION 2017-06-15 US disclosed
US-20150361317-A1 HOT MELT ADHESIVE LUCITE INTERNATIONAL UK LIMITED (GB) 2015-12-17 US disclosed
EP-2948486-A1 HOT MELT ADHESIVE Lucite International UK Limited (GB) 2015-12-02 EP disclosed
WO-2014114957-A1 HOT MELT ADHESIVE LUCITE INTERNATIONAL UK LIMITED (GB) 2014-07-31 WO disclosed
US-8382937-B2 Laminating adhesives based on triglyceride-derived polyols HENKEL CORPORATION (US) 2013-02-26 US disclosed
US-20110213077-A1 Hydroquinone-containing polyesters having improved whiteness SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US disclosed
US-20110204407-A1 Power LED device with a reflector made of aromatic polyester and/or wholly aromatic polyester SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-25 US disclosed
EP-2342766-A1 POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP disclosed
US-20060004175-A1 Method for producing a polyurethane prepolymer HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-01-05 US disclosed
EP-1498442-A2 Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof Daicel Chemical Industries, Ltd. (JP) 2005-01-19 EP disclosed
US-20040014860-A1 Chemically reactive adhesive comprising at least one micro encapsulated component HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-01-22 US disclosed
US-20040010092-A1 Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof WATANABE JUN (JP) 2004-01-15 US disclosed
US-6593434-B1 Condensation polymerization, esterification, melt mixing or kneading; high molecular weight, low crystallinity DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-15 US disclosed
EP-1120432-A1 PROCESS FOR THE PRODUCTION OF POLYESTER BLOCK COPOLYMERS, POLYESTER BLOCK COPOLYMER COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-08-01 EP disclosed
US-5618842-A TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES LIFEGROUP S.P.A. (IT) 1997-04-08 US disclosed
EP-0550008-A2 Use of N-acyl derivatives of aminoalcohols with polycarboxylic acids for the manufacture of a medicament for the treatment of pathologies relating to mast cells LIFEGROUP S.p.A. (IT) 1993-07-07 EP disclosed
US-5086104-A Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability POLYPLASTICS CO., LTD. (JP) 1992-02-04 US disclosed
US-4174455-A CHAIN EXTENSION, CROSSLINKING AND/OR CURINF OF POLYUREAS, POLYURETHANES, AND EPOXY RESINS CIBA-GEIGY CORPORATION (US) 1979-11-13 US disclosed