SCHEMBL21865335

SCHEMBL21865335

C=C(C)C(=O)OC1(C)OC(C(F)(F)F)(C(F)(F)F)CC1C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
XBP1 P17861 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
PAX8 Q06710 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21865340 0.89
SCHEMBL21865342 0.87
SCHEMBL21865334 0.80
SCHEMBL21865336 0.72 MAPT (0.32) MAPTXBP1HTTKMT2APAX8
SCHEMBL21864880 0.72 MAPT (0.33) MAPTXBP1HTTKMT2APAX8
SCHEMBL27846317 0.70 MAPT (0.36) MAPTXBP1HTTKMT2APAX8
SCHEMBL27863468 0.69 ALDH1A1 (0.39) ALDH1A1
SCHEMBL12213166 0.68 MAPT (0.36) MAPTXBP1HTTKMT2APAX8
SCHEMBL1834271 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL21864883 0.67 MAPT (0.32) MAPTXBP1HTTKMT2APAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200089116-A1 Fluorine-Containing Monomer, Fluorine-Containing Polymer, Pattern Forming Composition Using Same, and Pattern Forming Method of Same CENTRAL GLASS COMPANY, LIMITED (JP) 2020-03-19 US disclosed