Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 5/20 | 0.31 |
| ▸ | HTR2C | P28335 | 5/20 | 0.31 |
| ▸ | HTR2B | P41595 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607544 | 0.74 | HTR2C (0.40) | ARHTR2AHTR2CHTR2B | |
| SCHEMBL5675008 | 0.70 | HTR2C (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL15189277 | 0.66 | FFAR4 (0.42) | PTGS1PTGS2 | |
| SCHEMBL21866083 | 0.65 | AR (0.38) | ARHTR2AHTR2CHTR2B | |
| SCHEMBL16707469 | 0.65 | PTGS1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL23273109 | 0.63 | PTGS1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL21603434 | 0.63 | TP53 (0.44) | PTGS1PTGS2 | |
| SCHEMBL31607527 | 0.63 | MEN1 (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL19422711 | 0.62 | HSPA9 (0.33) | PTGS1PTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL16954442 | 0.61 | TRPV1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636643-A1 | NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2020-04-15 | — | — | EP | disclosed |