Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995212 | 0.78 | KMT2A (0.42) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL3414586 | 0.78 | CYP3A4 (0.39) | TDP1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL21865957 | 0.76 | AKR1B1 (0.53) | TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL21865880 | 0.76 | TDP1 (0.37) | TDP1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21865745 | 0.73 | TDP1 (0.34) | TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4652922 | 0.71 | MEN1 (0.33) | ALDH1A1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL2565042 | 0.71 | TAAR1 (0.38) | ALDH1A1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL30004999 | 0.71 | TAAR1 (0.38) | ALDH1A1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL1312057 | 0.71 | TDP1 (0.50) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL1246997 | 0.70 | CDK1 (0.47) | TDP1ALDH1A1GAAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636643-A1 | NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2020-04-15 | — | — | EP | disclosed |