Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576126 | 0.87 | POLH (0.33) | POLH | |
| SCHEMBL26562156 | 0.80 | MEN1 (0.57) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL22449722 | 0.75 | POLH (0.71) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL19943189 | 0.75 | CYP3A4 (0.70) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL13964377 | 0.74 | MEN1 (0.74) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL18575860 | 0.73 | — | — | |
| SCHEMBL19303497 | 0.72 | CYP3A4 (0.73) | POLHMEN1KMT2ACYP3A4ABCB1 | |
| SCHEMBL18576127 | 0.72 | MEN1 (0.36) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL13458641 | 0.72 | MEN1 (0.58) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL21347799 | 0.69 | MEN1 (0.74) | POLHMEN1KMT2ACYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139938-B1 | A MATRIX-METALLOPROTEINASE (MMP) INHIBITORY EXTRACT AND METHODS OF USE THEREOF | COMVITA LTD (NZ) | 2020-04-01 | — | — | EP | disclosed |