Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19316669 | 0.87 | TSHR (0.40) | TSHRALDH1A1SCN1ASCN2ASCN3A | |
| SCHEMBL15713250 | 0.80 | TSHR (0.53) | TSHRALDH1A1TP53SCN1ASCN2A | |
| SCHEMBL16193204 | 0.78 | TSHR (0.47) | TSHRALDH1A1TP53MAPTMEN1 | |
| SCHEMBL22058363 | 0.76 | TSHR (0.45) | TSHRALDH1A1TP53SCN1ASCN2A | |
| SCHEMBL2597547 | 0.76 | TSHR (0.47) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL12181907 | 0.76 | TSHR (0.51) | TSHRALDH1A1TP53KMT2AATM | |
| SCHEMBL21386597 | 0.74 | TSHR (0.34) | TSHRALDH1A1TP53SCN1ASCN2A | |
| SCHEMBL129437 | 0.73 | TSHR (0.62) | TSHRALDH1A1TP53TDP1L3MBTL1 | |
| SCHEMBL6285566 | 0.73 | SCN1A (0.59) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL18949239 | 0.73 | TSHR (0.46) | TSHRALDH1A1TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187515-B1 | POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER | TOKUYAMA DENTAL CORP (JP) | 2020-03-18 | — | — | EP | disclosed |