Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 9/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22646464 | 0.78 | SLC10A1 (0.49) | SLC10A1 | |
| SCHEMBL22646308 | 0.77 | ALDH1A1 (0.39) | SLC10A1PTGS2PTGS1MAPK1KMT2A | |
| SCHEMBL21869105 | 0.70 | SLC10A1 (0.35) | SLC10A1PTGS2PTGS1POLBKMT2A | |
| SCHEMBL22646287 | 0.69 | ALDH1A1 (0.36) | SLC10A1PTGS2PTGS1MAPK1POLB | |
| SCHEMBL21868845 | 0.64 | MEN1 (0.36) | SLC10A1PTGS2PTGS1POLBKMT2A | |
| SCHEMBL21868951 | 0.63 | ALDH1A1 (0.40) | PTGS2PTGS1MAPK1POLBKMT2A | |
| SCHEMBL24890429 | 0.61 | MAPK1 (0.38) | SLC10A1MAPK1POLBKMT2AALDH1A1 | |
| SCHEMBL21378308 | 0.61 | MAPK1 (0.60) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL22646427 | 0.60 | SLC10A1 (0.34) | SLC10A1POLBKMT2AALDH1A1MAPT | |
| SCHEMBL10917670 | 0.59 | CYP1A2 (0.64) | POLBKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628674-A1 | BICYCLIC NUCLEOCAPSID INHIBITOR AND USE OF SAME AS DRUG IN TREATMENT OF HEPATITIS B | Shanghai Longwood Biopharmaceuticals Co., Ltd. (CN) | 2020-04-01 | — | — | EP | disclosed |