Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869762 | 1.00 | KMT2A (0.60) | KMT2AGAAPOLBALDH1A1KDM4E | |
| SCHEMBL21869749 | 0.95 | KMT2A (0.52) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL21869750 | 0.93 | KMT2A (0.67) | KMT2AGAAALDH1A1KDM4EMAPT | |
| SCHEMBL21869759 | 0.92 | KMT2A (0.49) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL21869748 | 0.91 | HDAC1 (0.53) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL28669317 | 0.91 | HDAC1 (0.53) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL21869826 | 0.91 | HDAC1 (0.53) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL21869752 | 0.90 | KMT2A (0.47) | KMT2AHCRTR1HCRTR2HDAC1HDAC6 | |
| SCHEMBL21869800 | 0.90 | HCRTR2 (0.52) | KMT2AGAAPOLBALDH1A1CYP2C19 | |
| SCHEMBL21869753 | 0.90 | KMT2A (0.63) | KMT2AGAAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180552-B | Substituted 5-oxo pyrrolidine derivative and preparation method and application thereof | 沈阳药科大学 | 2021-10-26 | — | — | CN | disclosed |
| WO-2020063388-A1 | SUBSTITUTED 5-OXOPYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2020-04-02 | — | — | WO | disclosed |