Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437021 | 0.80 | PTPN1 (0.35) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL10797071 | 0.80 | PTPN1 (0.35) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL33901 | 0.80 | PTPN1 (0.35) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL10338803 | 0.80 | PTPN1 (0.35) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL10455206 | 0.77 | PTPN1 (0.33) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL211401 | 0.77 | PTPN1 (0.33) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL27833662 | 0.76 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL21869868 | 0.73 | ALOX15 (0.62) | PTPN1AKR1B1ALOX15ALOX12 | |
| SCHEMBL30848916 | 0.69 | PTPN1 (0.41) | PTPN1ALOX15ALOX12 | |
| SCHEMBL11230186 | 0.69 | CA1 (0.56) | PTPN1AKR1B1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021425-B2 | Polybrominated diphenyl-based flame retardant compounds | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200115308-A1 | POLYBROMINATED DIPHENYL-BASED FLAME RETARDANT COMPOUNDS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021425-B2 | Polybrominated diphenyl-based flame retardant compounds | PCBP1, FBL, PBRM1 | PTPN1 3306/4885AKR1B1 1179/4885ALOX15 2324/4885 |
| US-20200115308-A1 | POLYBROMINATED DIPHENYL-BASED FLAME RETARDANT COMPOUNDS | PCBP1, FBL, PBRM1 | PTPN1 3306/4885AKR1B1 1179/4885ALOX15 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.