Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 6/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869851 | 0.95 | CTPS1 (0.35) | CTPS1CYP2C9RORCCNR2DDR1 | |
| SCHEMBL21869896 | 0.92 | S1PR1 (0.37) | CYP2C9RORCDDR1S1PR1CYP3A4 | |
| SCHEMBL17824423 | 0.86 | MAPT (0.32) | CTPS1CYP2C9RORCIRAK4CYP3A4 | |
| SCHEMBL19684781 | 0.85 | S1PR1 (0.32) | CNR2LRRK2S1PR1 | |
| SCHEMBL19684786 | 0.85 | S1PR1 (0.31) | LRRK2S1PR1 | |
| SCHEMBL17824402 | 0.83 | JAK1 (0.34) | CYP2C9RORCDDR1IRAK4S1PR1 | |
| SCHEMBL17832721 | 0.83 | PIK3CA (0.35) | CYP2C9RORCDDR1AGPAT2S1PR1 | |
| SCHEMBL20632927 | 0.81 | BAZ2B (0.33) | CNR2DDR1LRRK2S1PR1 | |
| SCHEMBL29814438 | 0.81 | BAZ2B (0.33) | CNR2DDR1LRRK2S1PR1 | |
| SCHEMBL19684513 | 0.81 | LRRK2 (0.33) | RORCCNR2LRRK2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |