Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824429 | 0.90 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL17824402 | 0.89 | JAK1 (0.34) | S1PR1RORC | |
| SCHEMBL17824491 | 0.89 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL17824423 | 0.88 | MAPT (0.32) | RORC | |
| SCHEMBL17824483 | 0.87 | KCNH2 (0.33) | CNR2 | |
| SCHEMBL20633516 | 0.84 | LRRK2 (0.39) | LRRK2S1PR1RORCCNR2 | |
| SCHEMBL20633529 | 0.83 | LRRK2 (0.35) | LRRK2S1PR1RORCCNR2 | |
| SCHEMBL29814294 | 0.83 | LRRK2 (0.35) | LRRK2S1PR1RORCCNR2 | |
| SCHEMBL19684776 | 0.83 | PTGS2 (0.35) | LRRK2S1PR1RORCCNR2 | |
| SCHEMBL17824489 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308650-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-04 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308650-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | LRRK2 336/4885S1PR1 2300/4885RORC 1490/4885 |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | LRRK2 336/4885S1PR1 2300/4885RORC 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.