Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26674221 | 0.93 | HTR2C (0.46) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18911807 | 0.89 | HTR2A (0.43) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24110357 | 0.86 | HTR2C (0.48) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872537 | 0.85 | HTR2A (0.40) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872603 | 0.85 | HTR2C (0.40) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24110247 | 0.80 | HTR2C (0.48) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872466 | 0.80 | HTR2C (0.54) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10165538 | 0.79 | GRIN2B (0.55) | HTR2CHTR2AGRIN2B | |
| SCHEMBL24144086 | 0.79 | HTR2C (0.45) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872574 | 0.79 | HTR2C (0.45) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-3632897-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |