Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21872476 | 0.93 | HTR2C (0.46) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24110247 | 0.86 | HTR2C (0.48) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18911807 | 0.83 | HTR2A (0.43) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24144086 | 0.82 | HTR2C (0.45) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24110357 | 0.80 | HTR2C (0.48) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL26674263 | 0.80 | HTR2C (0.50) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872537 | 0.79 | HTR2A (0.40) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872603 | 0.79 | HTR2C (0.40) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24143180 | 0.79 | HTR2C (0.65) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL26674247 | 0.77 | HTR2C (0.41) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | NR1H2, NR1H3, NR1D1 | HTR2C 3626/4885HTR2A 3630/4885CYP1A2 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.