SCHEMBL2187591

SCHEMBL2187591

CCCCCC(Cc1ccccc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.55
FOLH1 Q04609 2/20 0.51
MMP2 P08253 11/20 0.51
MMP1 P03956 6/20 0.51
MMP3 P08254 6/20 0.51
CNR2 P34972 1/20 0.50
CYP1A2 P05177 1/20 0.50
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MMP7 P09237 2/20 0.48
BIRC2 Q13490 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28058533 0.98 CSNK1E (0.57) CSNK1EFOLH1MMP2MMP1MMP3
SCHEMBL22558568 0.98 CSNK1E (0.57) CSNK1EFOLH1MMP2MMP1MMP3
SCHEMBL7789683 0.98 CSNK1E (0.57) CSNK1EFOLH1MMP2MMP1MMP3
SCHEMBL28081007 0.98 CSNK1E (0.57) CSNK1EFOLH1MMP2MMP1MMP3
SCHEMBL2719254 0.95 CA1 (0.55) CSNK1EFOLH1MMP2MMP1MMP3
SCHEMBL18248569 0.90 FAAH (0.51) CSNK1EMMP2MMP1MMP3CNR2
SCHEMBL11357056 0.90 FAAH (0.51) CSNK1EMMP2MMP1MMP3CNR2
SCHEMBL18248575 0.90 FAAH (0.51) CSNK1EMMP2MMP1MMP3CNR2
SCHEMBL3662060 0.88 CYP1A2 (0.55) FOLH1CYP1A2
SCHEMBL2846532 0.88 CYP1A2 (0.55) FOLH1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2342180-A2 ORGANIC COMPOUNDS SUITABLE FOR MODULATING FRAGRANCE COMPOSITIONS Givaudan SA (CH) 2011-07-13 EP disclosed
WO-2010037244-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-04-08 WO disclosed